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Sr. Scientist, Antibody Discovery, Société CILOA

CILOA, a Biotech located in south of France, with a disruptive technology in the use of challenging proteins as immunogens is looking for an energetic Research Scientist with strong hands-on experience in immunology, cellular and molecular biology for a permanent position (CDI). Using state-of-the-art technologies, he will isolate antibody cDNA from single B cells. He will create a platform aiming to develop therapeutic antibodies. His success will contribute to our mission in the development of innovative therapeutics targeting so-called “undruggable” proteins involved in several types of pathologies.

Offered:

Opportunities to break new ground trusting you with responsibility early on and allowing you to fulfill your ambitions, and to draw your own career map that is responsive to your aspirations and priorities in life. Bring your imagination and skills to life!

Mission and key responsibilities:

  • Create and lead the platform of antibody generation using single B cell cloning strategy.

  • Design, execute and analyze experimental studies, propose creative solutions to troubleshoot problems, and proactively research new methods to improve processes.

  • Perform molecular and cellular biology experiments, including RT-PCR, PCR, recombinant DNA cloning, plasmid preps, bacterial transformation, mammalian cell culture, mammalian transfection for transient protein expression.

  • Conduct different assays: FACS, ELISA, Western blotting, BLI and SPR based Ab screening.

  • Collaborate and support other team members effectively to enhance productivity of the group and accomplish organizational goals.

  • Assist with process improvements by thinking critically about the design and execution of experiments, including automation, and SOP development.

  • With strong attention to detail, perform excellent record-keeping, time-management and organization to achieve group and company deliverables.

Required experience and skills:

  • Ph.D. in Molecular Biology, Immunology, or Cell Biology, with a minimum of 3+ years required; a post doc in relevant field a plus.

  • Experience in antibody generation strategies is desired; antibody engineering, optimization of effector function, affinity and biophysical properties a plus.

  • Experience with B cell biology with a solid background in mouse and human adaptive immune system, and in B/T cell differentiation.

  • Technical proficiency in molecular biology.

  • Mastery of sterile cell culture is a must.

  • Experience in multi-parameter/multi-color flow cytometry is desired. Knowledge of Flow cytometry based cell sorting is a plus.

  • Hands-on experience in antibody discovery methods, including advanced B-cell cloning is desired; hybridoma techniques, phage, yeast or/and mammalian display and other display technologies a plus.

  • Expertise in therapeutic antibody is desirable but not essential.

  • Familiarity with HTP automated recombinant protein expression is a plus.

  • Demonstrated ability to be proactive, diligent and reliable to meet deadlines. Excellent organization and planning skills.

  • Must be highly collaborative, team-oriented, yet with the ability to work independently.

  • Excellent interpersonal, verbal and written communication skills are required. Attention to detail and analytical.

  • Fluent English both written and verbal; French is a plus.

Applications should include: Send at contact(at)ciloa(dot)fr, a cover letter, CV, statement of research interests, and contact information for potential references.

Actualité

Eurobiomed Celebrates its new partnership with LINK-J !

All the best things happen in San Diego

 

LINK-J and Eurobiomed signed a Memorandum of Understanding on Monday 19th in San Diego, California at the Headquarter of BIOCOM, during the international biotech event Bio Convention.

Two lessons already have to be learned from this signature : Life Science brings vitality to international relations and a  Biotech Cluster Triumvira leaves no place for any deseases !

Indeed, LINK-J, the young but very promising Cluster of Tokyo gathering some of the most successfull pharmaceutical companies and biotech start-ups signed an MOU with BIOCOM, a 900+ members advocating Cluster of California, in May, 2016. Since then, both parties have cooperated some events such as bringing their members to other party’s seminars held in San Diego or Tokyo. LINK-J has expanded its relationship with University of Califolnia, San Diego as well.

Besides Eurobiomed, one of the greatest Life Science french Cluster, with a strong European network and open doors to the African Continent, found many similarities with BIOCOM’s ecosystem such as the collaborative spirit of the companies and the strong start-up and SME’s network. They therefore signed a MoU  in San Diego, on June, 2014. Many successfull actions have been realised so far, such as the participation to joint events but also the organization of delegations that led companies to create new partnerships and subsidiaries.

Thanks to BIOCOM and his CEO Joe Panetta, LINK-J and Eurobiomed could meet during the Global Life Science Partnering Conference hosted in March 2017 in San Diego and have a first meaningfull meeting.

On each side the common will to support companies and scientific institutes to grow international and improve their R&D projects, was obvious but the challenge is always to find THE good partner to enable long term trustbased relationships. A MoU is just a piece of paper without ambitous people behind it willing to work hard and to always reinvent new ways of collaborating.

Many fruitful exchanges have then led the Tokyo Cluster to visit Eurobiomed two months after to understand better each others’ functioning and ecosystem. With such a strong convergence of ideas and dreams for the future of Life Science the signature of a MoU became obvious and San Diego would be the place where, for the third time, all would begin.

Thus, surrounded by their mutual team, Mr. Akihiko Soyama, President and CEO of LINK-J and Xavier Tabary, President of Eurobiomed signed a MoU on June 19th, 2017. They both committed themselves in providing services to each other’s members, exchange publications, materials and informations, do cooperative activities, events, progams and visits for the next five years.

Yet, a first delegation of LINK-J with Biocom is scheduled for October 30th until November 3rd. Many companies are expected from the three Clusters in order to network and create new life sciences projects !