CILOA, a Biotech located in south of France, with a disruptive technology in the use of challenging proteins as immunogens is looking for an energetic Research Scientist with strong hands-on experience in immunology, cellular and molecular biology for a permanent position (CDI). Using state-of-the-art technologies, he will isolate antibody cDNA from single B cells. He will create a platform aiming to develop therapeutic antibodies. His success will contribute to our mission in the development of innovative therapeutics targeting so-called “undruggable” proteins involved in several types of pathologies.
Opportunities to break new ground trusting you with responsibility early on and allowing you to fulfill your ambitions, and to draw your own career map that is responsive to your aspirations and priorities in life. Bring your imagination and skills to life!
Mission and key responsibilities:
Create and lead the platform of antibody generation using single B cell cloning strategy.
Design, execute and analyze experimental studies, propose creative solutions to troubleshoot problems, and proactively research new methods to improve processes.
Perform molecular and cellular biology experiments, including RT-PCR, PCR, recombinant DNA cloning, plasmid preps, bacterial transformation, mammalian cell culture, mammalian transfection for transient protein expression.
Conduct different assays: FACS, ELISA, Western blotting, BLI and SPR based Ab screening.
Collaborate and support other team members effectively to enhance productivity of the group and accomplish organizational goals.
Assist with process improvements by thinking critically about the design and execution of experiments, including automation, and SOP development.
With strong attention to detail, perform excellent record-keeping, time-management and organization to achieve group and company deliverables.
Required experience and skills:
Ph.D. in Molecular Biology, Immunology, or Cell Biology, with a minimum of 3+ years required; a post doc in relevant field a plus.
Experience in antibody generation strategies is desired; antibody engineering, optimization of effector function, affinity and biophysical properties a plus.
Experience with B cell biology with a solid background in mouse and human adaptive immune system, and in B/T cell differentiation.
Technical proficiency in molecular biology.
Mastery of sterile cell culture is a must.
Experience in multi-parameter/multi-color flow cytometry is desired. Knowledge of Flow cytometry based cell sorting is a plus.
Hands-on experience in antibody discovery methods, including advanced B-cell cloning is desired; hybridoma techniques, phage, yeast or/and mammalian display and other display technologies a plus.
Expertise in therapeutic antibody is desirable but not essential.
Familiarity with HTP automated recombinant protein expression is a plus.
Demonstrated ability to be proactive, diligent and reliable to meet deadlines. Excellent organization and planning skills.
Must be highly collaborative, team-oriented, yet with the ability to work independently.
Excellent interpersonal, verbal and written communication skills are required. Attention to detail and analytical.
Fluent English both written and verbal; French is a plus.
Applications should include: Send at contact(at)ciloa(dot)fr, a cover letter, CV, statement of research interests, and contact information for potential references.
BIOREZO Spécial Chine
Biorézo™ Join us for an introduction to WuXi AppTec, China’s leading R&D service partner and a gateway to the Chinese market
Eurobiomed is pleased to invite you to a great opportunity to discover and learn more about the Chinese Market for current and future development.
WuXi AppTec, the leading global contract research outsourcing provider, serving worldwide pharmaceutical, biotech and medical device industries, will be performing a Roadshow in Marseille in order to present its open access technology platform and meet with Eurobiomed members and partners.
WuXi AppTec wishes to facilitate and strengthen connections between the French innovative healthcare sector and the Chinese commercial and academic network.
Through its technological platform, WuXi AppTec will also focus on the support or collaboration that can be offered to early stage companies or innovative projects.
SAVE THE DATE
15th June 2017 - 16h30,
Ecole de Management EMD
Rue Joseph Biaggi, Marseille
Attractiveness of Chinese Market
Wuxi AppTec: core activities and opportunities
Cocktail and networking
For more information: Nicolas SAINTE-FOIE - +33 6 61 78 12 53 - nicolas.saintefoie(at)eurobiomed.org
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