Partager cette page


Sr. Scientist, Antibody Discovery, Société CILOA

CILOA, a Biotech located in south of France, with a disruptive technology in the use of challenging proteins as immunogens is looking for an energetic Research Scientist with strong hands-on experience in immunology, cellular and molecular biology for a permanent position (CDI). Using state-of-the-art technologies, he will isolate antibody cDNA from single B cells. He will create a platform aiming to develop therapeutic antibodies. His success will contribute to our mission in the development of innovative therapeutics targeting so-called “undruggable” proteins involved in several types of pathologies.

Offered:

Opportunities to break new ground trusting you with responsibility early on and allowing you to fulfill your ambitions, and to draw your own career map that is responsive to your aspirations and priorities in life. Bring your imagination and skills to life!

Mission and key responsibilities:

  • Create and lead the platform of antibody generation using single B cell cloning strategy.

  • Design, execute and analyze experimental studies, propose creative solutions to troubleshoot problems, and proactively research new methods to improve processes.

  • Perform molecular and cellular biology experiments, including RT-PCR, PCR, recombinant DNA cloning, plasmid preps, bacterial transformation, mammalian cell culture, mammalian transfection for transient protein expression.

  • Conduct different assays: FACS, ELISA, Western blotting, BLI and SPR based Ab screening.

  • Collaborate and support other team members effectively to enhance productivity of the group and accomplish organizational goals.

  • Assist with process improvements by thinking critically about the design and execution of experiments, including automation, and SOP development.

  • With strong attention to detail, perform excellent record-keeping, time-management and organization to achieve group and company deliverables.

Required experience and skills:

  • Ph.D. in Molecular Biology, Immunology, or Cell Biology, with a minimum of 3+ years required; a post doc in relevant field a plus.

  • Experience in antibody generation strategies is desired; antibody engineering, optimization of effector function, affinity and biophysical properties a plus.

  • Experience with B cell biology with a solid background in mouse and human adaptive immune system, and in B/T cell differentiation.

  • Technical proficiency in molecular biology.

  • Mastery of sterile cell culture is a must.

  • Experience in multi-parameter/multi-color flow cytometry is desired. Knowledge of Flow cytometry based cell sorting is a plus.

  • Hands-on experience in antibody discovery methods, including advanced B-cell cloning is desired; hybridoma techniques, phage, yeast or/and mammalian display and other display technologies a plus.

  • Expertise in therapeutic antibody is desirable but not essential.

  • Familiarity with HTP automated recombinant protein expression is a plus.

  • Demonstrated ability to be proactive, diligent and reliable to meet deadlines. Excellent organization and planning skills.

  • Must be highly collaborative, team-oriented, yet with the ability to work independently.

  • Excellent interpersonal, verbal and written communication skills are required. Attention to detail and analytical.

  • Fluent English both written and verbal; French is a plus.

Applications should include: Send at contact(at)ciloa(dot)fr, a cover letter, CV, statement of research interests, and contact information for potential references.

Actualité

Les Rencontres AMFT Connect to the world !

Une journée 100 % consacrée à l'internationale pour s'informer, découvrir, échanger !

JOIN US ! 10h - 22h

AMFT TOUR 9h - 12h

Portes-ouvertes des structures d'accompagnement
entre Aix-en-Provence et Marseille

Incubateurs, pépénières, accélérateurs, pôles de compétitivité accueillent dans leurs locaux les startups et porteurs de projets pour présenter leur offre de services et parler de l'international sous forme de mini conférences, ateliers, témoignages...

PROGRAMME

EUROBIOMED
8 rue Sainte-Barbe - 13001 Marseille

9h30 - 11h30 Entreprises biotech et medtech, boostez votre développement aux US, via la Californie !

Le marché américain est parmi les plus attractifs mais aussi les plus concurrentiels dans l'univers des sciences de la vie. Eurobiomed et ses partenaires vous présenteront les actions mises en place pour y accélérer votre développement.

 

Inscription par mail ICI

 

DISCOVERY MEETINGS 14h - 17h30

Découvertes des acteurs de l'international
World Trade Center - Marseille

Présentation des différentes structures impliquées dans l'internationalisation des entreprises. Espace dédié à la rencontre avec chaque structure et ateliers pratiques sur inscription.

A ne pas manquer, à 15h30
Décryptage : "L'intelligence économique au service des entreprises"
par Christophe Clarinard et Dominique Ciravegna

PROGRAMME

 

Osons l'international!
World Trade Center - Marseille

18h . Accueil

18h30
Introduction - Pascal Lorne, Président
Présentation des actions AMFT - Isadora Bigourdan, Vincent Berge et Lionel Minassian - Vice Présidents AMFT

Table ronde d'entrepreneurs
Marc Schillaci - CEO OxatisEric Elkaim - CEO Alert Gasoil - Label Pass French Tech
David Sussmann - président de Seafoodia et de la Fondation Pure Océan

Lionel Baraban - CEO Famoco

19h30 - 22h . Cocktail networking

INSCRIVEZ-VOUS

 

Partenaires officiels: et